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Our group's research focuses on developing and
utilizing statistical mechanics theories, bioinformatic, and
simulation methods to explain and predict the behavior of biologically
interesting macromolecules. The current research program aimed at the
understanding of the molecular mechanisms and bioinformatic studies of
protein folding, stability, and binding of ligands, peptides, and DNA. The long-term goal of the
proposed research is to elucidate the relations between the sequence,
structure, and function of proteins and to uncover the molecular
mechanisms underlying different diseases. This will be accomplished by designing simple (yet
realistic) models and by developing statistical mechanics theories and bioinformatic
tools.
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See Publications for Details |