Point Mutation Stability Change Prediction Using DFIRE Potential

Mutation Stability Change Prediction

usage: for example, in pdb file 1jev, there are two chains: A,B. If one wants to know the Mutation Stability Change of 15th residue LEU on chain A, then the input and output are the following:

Input
	Please input chain name:A
	Please input residue sequence position #: 15
Output

	CYS	MET	PHE	ILE	LEU	VAL	TRP	TYR	ALA	GLY	THR	SER	GLN	ASN	GLU	ASP	HIS	ARG	LYS	PRO
15 LEU	1.78	1.16	-0.29	0.39	0.00	1.24	-1.05	0.97	3.29	4.40	2.90	3.84	3.12	3.50	3.89	3.92	2.98	3.06	3.71	3.80
	-	-	+	-	-	-	+	+	-	-	-	-	+	-	+	-	+	+	+	-

Note:
+ : mutation from a small residue to a large one. The result is not reliable.
- : mutation from a large residue to a small one. The result is more reliable.
The unit of output numbers is kcal/mol.

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since 05/04/03

Please input the PDB file:
Or input the PDB ID:
Please input chain name:	default is the first chain
Please input residue sequence position # :